Enhanced anti‐angiogenic activity of novel melatonin‐like agents
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چکیده
منابع مشابه
Phosphomimetic mutants of pigment epithelium-derived factor with enhanced antiangiogenic activity as potent anticancer agents.
Pigment epithelium-derived factor (PEDF) is an endogenous inhibitor of angiogenesis and a promising anticancer agent capable of suppressing solid tumor growth in animal cancer models. We have previously shown that PEDF can be phosphorylated and that distinct phosphorylation states of this factor differentially regulate its physiologic function. Here, we report that phosphomimetic mutants of PED...
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ژورنال
عنوان ژورنال: Journal of Pineal Research
سال: 2021
ISSN: 0742-3098,1600-079X
DOI: 10.1111/jpi.12739